Recruiting MS, PhD candidates (for 2024 Spring Semester)
석사, 석박통합, 박사과정 학생 OO명을 모집합니다. 한국 학생, 외국 학생 모두 환영합니다.
We are recruiting combined MS/PhD or PhD candidates. Korean or foreign applicants are welcome to join in our lab.
■ 문랩 연구원 인터뷰 Members’ Interview
https://youtu.be/xFmm_UxEFWM?si=Kv-DpNOOgZcAxnkJ
■ 교육의 목표 Goal of Education
우리 실험실의 교육 목표는 석/박사 학위 취득후 국내외 업체, 교직 및 공직에 취업을 준비하는 우수한 학생들에게 경쟁력을 갖추도록 잘 교육하여 좋은 미래를 맞을 수 있도록 발판을 마련해 주는 것입니다.
Our goal is to educate students to have competitiveness and establish a foothold for their future job in Universities, public services, or industries.
■ 교육 분야 Area of Education
가장 수요가 많은 종양생물학과 분자생물학입니다.
Cancer biology and molecular biology which are recently in great demand.
■ 연구실 소개 Introduction of Our Lab
책임연구자는 차의과학대학 혈액종양내과 교수입니다. 연세대학교 의학과에서 박사를 취득하고 미국 국립보건원에서 박사후 연구과정을 마쳤습니다.
PI is a medical oncologist-scientist, who got PhD degree in Yonsei University Medical College. Then PI had postdoctoral training in the NIH, USA.
본 연구실은 국가지정 연구중심병원 랩으로 2016년부터 9년짜리 연구중심병원 국가과제인 "효능증대 융합형 면역세포치료 플랫폼 개발’ 이라는 연구를 수행하고 있습니다. 또한 유방암, 난소암 및 전립선암 표적치료제의 내성기전 및 신약 개발에 중점을 둔 연구를 하고 있습니다.
Our lab is a Nationally designated 'Research-driven Hospital' lab. We are performing a project titled 'Development of anticancer cellular immunotherapy platform' under 9-year national grant since 2016. In addition, we focus on resistance mechanisms of targeted therapies and development of novel therapeutics in breast, ovary, and prostate cancer.
연구원 구성: 박사후 연구원 1, 박사생 2, 석박통합생 1
Lab members: Postdoctoral scientist 1, PhD candidate 2, MS/PhD candidate 1
■ 대표 논문 Representative Papers
-Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model. JITC 2020; 8: e001513
-Combined CDK2 and CDK4/6 Inhibition Overcomes Palbociclib Resistance in Breast Cancer by Enhancing Senescence. Cancers (Basel) 2020; 12: 3566
-LAMC2 enhances the metastatic potential of lung adenocarcinoma. Cell Death Differ 2015; 22:1341
-CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance. J Clin Invest 2014; 124:3003
-Molecular mechanisms of resistance to CDK4/6 inhibitors in breast cancer: A review. Int J Cancer 2019; 145: 1179
-IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells. 2019; J Immunother Cancer 2019: 7:168
■ 본교 대학원 소개 Introduction of Graduate School of CHA University
본교 대학원 학위과정은 판교 테크노밸리에 위치한 차바이오컴플렉스를 캠퍼스로 사용하며 최신식 연구시설과 동물연구시설을 갖추었습니다. 석사, 박사, 석박사 통합과정이 개설되어 있고, 의생명과학 연관 분야를 전공하신 50여명의 교수님들로 구성된 대규모 학위과정이며, 졸업시 이학석사(MS)/이학박사(PhD)가 수여됩니다.
CHA Bio Complex, located in the Pangyo Techno-Valley, is the main campus of our graduate school. CHA Bio Complex has the latest research facilities and animal facilities. There are MS, PhD, and combined MS/PhD courses in our graduate school. More than 50 professors who major in life science-related fields teach students
■실험실 연구내용 Research Fields
▶Main research topics
-Developmeent of combinators to enhance immune checkpoint
inhibitors
-Mechanisms
of resistance to CDK4/6 inhibitor and development of overcoming strategies
-Mechanisms of resistance to PARP inhibitor and development of overcoming strategies
-Developmeent of ESR1 mutation inhibitor in breast cancer
▶Other research topics
-In vivo efficacy test of anticancer drugs using PDTX and humanized mice
-Discovery of novel cancer therapeutic target through omics technologies
▶Experimental techniques required
Cell culture, MTT, western blotting, mice experiments (xenografting, tumor size measurement, IP, IV, oral injection), FACS, RT-PCR, IHC/IF, siRNA transfection, sample preps for omics experiments, interpretation of omics results, etc.
■경제적 지원 Financial Support
수업료 (100%)와 월급여; 월급여는 지원자가 어떤 실험 스킬을 가지고 있느냐에 달려있습니다.
Tuition fee (100%) plus monthly salary; The amount of salary depends on how experienced experimetal skills he/she has.
■Application process
▶Documents required
-이력서 CV (including experimental skills)
-졸업증명서 Graduation certificate (대학교 University, 석사 Master)
-성적표 Transcript (대학교 University, 석사 Master)
-IELTS result (IELTS 영어시험 점수)
-논문 Papers (학위논문 Thesis, 출판된 논문 Published papers)
-추천서는 면접 이후에 제출 가능. Recommendation letters may be submitted after interview
▶Contact
문용화 교수, Yong Wha Moon, MD, PhD
Email: ymoon@cha.ac.kr
Moonlab homepage: http://moonlab.kr/
Office phone: +82-31-780-3436
